Products

    Enfamil NeuroPro™ Infant

    The only infant formula brand with a brain-building MFGM and DHA blend previously found only in breast milk

    Indication

    Enfamil NeuroPro Infant is a 20 Cal/fl oz milk-based, iron-fortified, routine formula for full-term infants 0–12 months. Enfamil NeuroPro Infant has a fat-protein blend of MFGM and DHA previously found only in breast milk*. Emerging evidence from a recent clinical study showed MFGM in formula supports cognitive development similar to breast milk†. Enfamil NeuroPro Infant is patterned after mature breast milk‡.

    * In amounts supported by clinical research.
    † As measured by Bayley-III cognitive score at months in a different formula with MFGM added as an ingredient.
    ‡ Comparison based on whey:casein ration of typical mature breast milk (15 days to 6 month after birth)1.</small

    Reference:
    1. Timby N, Domellöf E, Hernell O, et al. Neurodevelopment, nutrition, and growth until 12 mo of age in infants fed a low-energy, low-protein formula supplemented with bovine milk fat globule membranes: a randomized controlled trial. Am J Clin Nutr.

    Ingredients

    Ingredients: Powder: Nonfat milk, lactose, vegetable oil (palm olein, coconut, soy and high oleic sunflower oils), whey protein concentrate, whey protein-lipid concentrate (milk)§ and less than 2%: galactooligosaccharides||, polydextrose||, Mortierella alpina oil, Schizochytrium sp. oil#, calcium carbonate, potassium citrate, potassium chloride, ferrous sulfate, calcium phosphate, sodium chloride, magnesium oxide, zinc sulfate, cupric sulfate, manganese sulfate, potassium iodide, sodium selenite, soy lecithin, inositol, choline chloride, ascorbic acid, niacinamide, calcium pantothenate, vitamin A palmitate, riboflavin, thiamin hydrochloride, vitamin D3, vitamin B6 hydrochloride, folic acid, vitamin K1, biotin, vitamin B12, vitamin E acetate, nucleotides (cytidine 5’-monophosphate, disodium uridine 5’-monophosphate, adenosine 5’-monophosphate, disodium guanosine 5’-monophosphate), taurine, L-carnitine.

     

    Ingredients: Ready To Use (2 & 6 fl oz Nursette® bottles): Water, nonfat milk, lactose, vegetable oil (palm olein, soy, coconut and high oleic sunflower oils) and less than 2%: whey protein-lipid concentrate (milk)§, galactooligosaccharides||, polydextrose||, Mortierella alpina oil, Schizochytrium sp. oil#, whey protein concentrate, potassium citrate, calcium carbonate, calcium phosphate, magnesium phosphate, calcium chloride, sodium chloride, ferrous sulfate, zinc sulfate, cupric sulfate, manganese sulfate, potassium iodide, sodium selenite, mono- and diglycerides, ascorbic acid, sodium ascorbate, vitamin E acetate, niacinamide, calcium pantothenate, vitamin A palmitate, thiamin hydrochloride, riboflavin, vitamin B6 hydrochloride, folic acid, vitamin K1, biotin, vitamin D3, vitamin B12, soy lecithin, carrageenan, choline chloride, inositol, nucleotides (cytidine 5’-monophosphate, disodium uridine 5’-monophosphate, adenosine 5’-monophosphate, disodium guanosine 5’-monophosphate), taurine, L-carnitine.

     

    Ingredients: Ready To Use (32 fl oz bottle**): Water, nonfat milk, lactose, vegetable oil (palm olein, soy, coconut and high oleic sunflower oils) and less than 2%: whey protein-lipid concentrate (milk)§, galactooligosaccharides||, polydextrose||, Mortierella alpina oil||||, Schizochytrium sp. oil#, whey protein concentrate, potassium citrate, calcium carbonate, calcium chloride, magnesium phosphate, sodium chloride, calcium phosphate, ferrous sulfate, zinc sulfate, cupric sulfate, manganese sulfate, sodium selenite, potassium iodide, mono- and diglycerides, soy lecithin, ascorbic acid, sodium ascorbate, vitamin E acetate, niacinamide, calcium pantothenate, vitamin A palmitate, thiamin hydrochloride, riboflavin, vitamin B6 hydrochloride, folic acid, vitamin K1, biotin, vitamin B12, carrageenan, choline chloride, inositol, nucleotides (cytidine 5’-monophosphate, adenosine 5’-monophosphate, disodium uridine 5’-monophosphate, disodium guanosine 5’-monophosphate), vitamin D3, taurine, L-carnitine.

     

    § A source of MFGM (milk fat globule membrane).
    || A type of prebiotic.
    A source of arachidonic acid (ARA).
    # A source of docosahexaenoic acid (DHA).
    ** Nutrient profile subject to change.

    POTENTIAL ALLERGENS

    Enfamil NeuroPro™ Infant contains milk and soy.

    Nutrients

    (Normal Dilution)

    Per 100 Calories (5 fl oz)

    Per 100 mL

    Per 100 grams Powder (500 Cal)

    Protein, g

    2

    1.35

    10.2

    Fat, g

    5.3

    3.6

    27

    Linoleic acid, mg

    780

    530

    4000

    Carbohydrate, g

    11.3

    7.6

    58

    Water, g

    133

    90

    2.4

    Vitamins/Other Nutrients

    Vitamin A, IU

    300

    200

    1530

    Vitamin D, IU (Pwd)††

    75

    51

    380

    Vitamin E, IU

    2

    1.35

    10.2

    Vitamin K, mcg

    9

    6.1

    46

    Thiamin (Vitamin B1), mcg

    80

    54

    410

    Riboflavin (Vitamin B2), mcg

    140

    95

    710

    Vitamin B6, mcg

    60

    41

    310

    Vitamin B12, mcg

    0.3

    0.2

    1.53

    Niacin, mcg

    1000

    680

    5100

    Folic acid (Folacin), mcg

    16

    10.8

    82

    Pantothenic acid, mcg

    500

    340

    2600

    Biotin, mcg

    3

    2

    15.3

    Vitamin C (Ascorbic acid), mg

    12

    8.1

    61

    Choline, mg

    24

    16.2

    122

    Inositol, mg

    24

    16.2

    122

    Minerals

    		      

    Calcium, mg

    78

    53

    400

    Phosphorus, mg

    43

    29

    220

    Magnesium, mg

    8

    5.4

    41

    Iron, mg

    1.8

    1.22

    9.2

    Zinc, mg

    1

    0.68

    5.1

    Manganese, mcg

    15

    10.1

    77

    Copper, mcg

    75

    51

    380

    Iodine, mcg

    15

    10.1

    77

    Selenium, mcg

    2.8

    1.89

    14.3

    Sodium, mg

    27

    18.3

    138

    Potassium, mg

    108

    73

    550

    Chloride, mg

    63

    43

    320

    * Vitamin D levels for ready-to-use are: 70 IU, 100kcal and 471/100 mL.

    Product nutrient values and ingredients are subject to change. Please see product label for current information.

    Nutrient Density

    20 Calories/fl oz

    Protein (% Calories)

    8

    Whey:Casein Ratio

    60:40

    Fat (% Calories)

    48

    Carbohydrate (% Calories)

    44

    Potential Renal Solute Load (mOsm/100 Calories)1

    18.6

    Potential Renal Solute Load (mOsm/100 mL)1

    12.5

    Osmolality (mOsm/kg water)

    300

    Osmolarity (mOsm/L)

    270

    Lactose-free

    No

    Reference:
    1. Fomon SJ, Ziegler EE. Renal solute load and potential renal solute load in infancy. J Pediatr. 1999;134:11-14.

    Dilutions and Preparation

    DILUTION TABLES FOR ENFAMIL NEUROPRO INFANT

    Mixing instructions by the scoop

    Download dilution information

    Mixing instructions for Nursette® bottle or breast milk

    Download dilution information

    POWDER

    A baby’s health depends on carefully following the instructions below. Use only as directed by a medical professional. Proper hygiene, preparation, dilution, use and storage are important when preparing infant formula. Powdered infant formulas are not sterile and should NOT be fed to premature infants or infants who might have immune problems unless directed and supervised by a doctor. Discuss with parents which formula is appropriate for the baby.

    Discuss with parents whether they need to use cooled, boiled water for mixing and whether they need to boil clean utensils, bottles and nipples in water before use.

    WARNING: Do not use a microwave oven to warm formula. Serious burns may result.

    Refer to the product label for the most accurate information.

    Failure to follow these instructions could result in severe harm. Once prepared, infant formula can spoil quickly. Either feed immediately or cover and store in refrigerator at 35–40°F (2–4°C) for no longer than 24 hours. Do not use prepared formula if it is unrefrigerated for more than a total of 2 hours. Do not freeze prepared formula. After feeding begins, use formula within 1 hour or discard.

    1. Wash hands thoroughly with soap and water before preparing formula.
    2. Pour the desired amount of water into the bottle. Add powder.
    3. Cap bottle and SHAKE WELL.

    Use the following chart for correct amounts of water and powder.

    To Make*

    Water

    Powder

    Weight

    2 fl oz bottle

    2 fl oz

    1 unpacked level scoop

    8.8 g

    4 fl oz bottle

    4 fl oz

    2 unpacked level scoops

    17.6 g

    8 fl oz bottle

    8 fl oz

    4 unpacked level scoops

    35.2 g

    *Each scoop adds about 0.2 fl oz to the amount of prepared formula.

    READY-TO-FEED

    A baby’s health depends on carefully following the instructions below. Use only as directed by a medical professional. Proper hygiene, preparation, dilution, use and storage are important when preparing infant formula. Discuss with parents which formula is appropriate for the baby.

    2 & 6 fl oz Nursette® Bottles

    1. Inspect each bottle for signs of damage.
    2. Wash hands thoroughly with soap and water before preparing bottle for feeding.
    3. SHAKE BOTTLE WELL and remove cap.
    4. Attach nipple unit (not included).

    WARNING: Do not use a microwave oven to warm formula. Serious burns may result.

    Failure to follow these instructions could result in severe harm. Opened bottles can spoil quickly. Either feed immediately or replace cap and store in refrigerator at 35–40°F (2–4°C) for no longer than 24 hours. Do not use opened bottle if it is unrefrigerated for more than a total of 2 hours. Do not freeze. After feeding begins, use formula within 1 hour or discard.

    32 fl oz Bottles

    1. Wash hands thoroughly with soap and water before preparing feeding bottles.
    2. SHAKE BOTTLE WELL, remove protective seal around cap, remove cap and foil seal. Replace cap.
    3. Pour into feeding bottle(s).

    WARNING: Do not use a microwave oven to warm formula. Serious burns may result.

    Failure to follow these instructions could result in severe harm. Opened bottles and prepared formula can spoil quickly. Either feed immediately or cover and store in refrigerator at 35–40°F (2–4°C) for no longer than 48 hours. Do not use opened bottle and/or prepared formula if they are unrefrigerated for more than a total of 2 hours. Do not freeze prepared formula. After feeding begins, use prepared formula within 1 hour or discard.

    SINGLE-SERVE POWDER PACKETS

    A baby’s health depends on carefully following the instructions below. Use only as directed by a medical professional. Proper hygiene, preparation, dilution, use and storage are important when preparing infant formula. Discuss with parents which formula is appropriate for the baby.

    1. Wash hands thoroughly with soap and water before preparing formula.
    2. Pour desired amount of water into bottle. Pour entire contents of packet(s) into bottle.
    3. Cap bottle and SHAKE WELL.

    WARNING: Do not use a microwave oven to warm formula. Serious burns may result.

    Failure to follow these instructions could result in severe harm. Once prepared, infant formula can spoil quickly. Either feed immediately or cover and store in refrigerator at 35–40°F (2–4°C) for no longer than 24 hours. Do not use prepared formula if it is unrefrigerated for more than a total of 2 hours. Do not freeze prepared formula. After feeding begins, use formula within 1 hour or discard.

    Use the chart below for correct amounts of water and powder.

    To Make*

    Water

    Powder

    Weight

    4 fl oz bottle

    4 fl oz

    1 packet

    17.6 g

    8 fl oz bottle

    8 fl oz

    2 packets

    35.2 g

    *Each packet adds about 0.4 fl oz to the amount of prepared formula.

    Product Forms and Ordering Information

    ENFAMIL NEUROPRO INFANT IS AVAILABLE IN POWDER AND READY-TO-FEED-LIQUID

    Coding systems and reimbursement allowable rates vary by payer:

    • Medicare Part B uses HCPCS (Healthcare Common Procedure Coding System) to group products
    • Medicaid systems vary by state; some use HCPCS while others use NDC format code or systems of their own—contact your state provider for more information
    • Private health insurance and managed care companies may use HCPCS, NDC format code or their own system—contact your provider for more information

    Enfamil NeuroPro™ Infant, Powder Refill
    Item #: 163205
    Description: Powder, Refill
    Unit Size: 31.4 oz box
    Calories/Unit: 4500
    Product Yield/Unit (fl oz): 225
    Case: 4 boxes per case
    HCPCS Code: B4158
    NDC Format Code: 00087-5121-11

     

    Enfamil NeuroPro™ Infant, Powder (28.3 oz can)
    Item #: 163204
    Description: Powder
    Unit Size: 28.3 oz can
    Calories/Unit: 4040
    Product Yield/Unit (fl oz): 202
    Case: 4 cans per case
    HCPCS Code: B4158
    NDC Format Code: 00087-5121-09

     

    Enfamil NeuroPro™ Infant, Powder (20.7 oz tub)
    Item #: 163203
    Description: Powder
    Unit Size: 20.7 oz tub
    Calories/Unit: 2960
    Product Yield/Unit (fl oz): 148
    Case: 6 tubs per case
    HCPCS Code: B4158
    NDC Format Code: 00087-5121-07

     

    Enfamil NeuroPro™ Infant, Single-Serve Powder Packets
    Item #: 163201
    Description: Single-Serve Powder Packets
    Unit Size: 17.6 g stick packs (14 per carton)
    Calories/Unit: 1120
    Product Yield/Unit (fl oz): 56
    Case: 4 cartons per case
    HCPCS Code: B4158
    NDC Format Code: 00087-5121-03

     

    Enfamil NeuroPro™ Infant, Ready-to-Feed (2 fl oz Nursette® bottle)
    Item #: 171601
    Description: RTF
    Unit Size: 2 fl oz bottle
    Calories/Unit: 40
    Product Yield/Unit (fl oz): 2
    Case: 48 bottles per case
    HCPCS Code: B4158
    NDC Format Code: 00087-5121-29

     

    Enfamil NeuroPro™ Infant, Ready-to-Feed (6 fl oz Nursette® bottle)
    Item #: 171901
    Description: RTF
    Unit Size: 6 fl oz bottle
    Calories/Unit: 120
    Product Yield/Unit (fl oz): 6
    Case: 24 bottles per case
    HCPCS Code: B4158
    NDC Format Code: 00087-5121-33

     

    Enfamil NeuroPro™ Infant, Ready-to-Feed (32 fl oz bottle)
    Item #: 172202
    Description: RTF
    Unit Size: 32 fl oz bottle
    Calories/Unit: 640
    Product Yield/Unit (fl oz): 32
    Case: 6 bottles per case
    HCPCS Code: B4158
    NDC Format Code: 00087-5121-41

    PRODUCT BENEFITS

    The only formula to offer a revolutionary fat-protein blend of milk fat globule membrane (MFGM) and DHA previously only found in breast milk*

    Infant formula that has MFGM & DHA is clinically shown to:

    • Provide cognitive outcomes like breast milk†2,3
    • Support immune health like breast milk‡4,5
    • Be a safe and well-tolerated source of nutrition2

    DHA at the clinically proven* amount of 0.32% of total fatty acids, the same amount as the worldwide breast milk average,1,† and double the amount found in the leading competitor’s product‡

    • Clinically provento support mental, visual and immune system development
    • Clinically shown to improve long-term cognitive outcomes through 5 years of age2
    • Shown to improve respiratory health through the first 3 years of life when infants were fed through 12 months3

    A Natural Defense® Dual Prebiotic blend of GOS (galactooligosaccharides) and PDX (polydextrose) at 4 g/L is designed to:

    • Support immune health by promoting the growth of beneficial bacteria (bifidobacteria and lactobacilli)4,5
    • Promote soft stools similar to those reported for breastfed infants6

    Additional product features:

    • Infant formula that has MFGM and DHA is clinically shown to be a safe and well-tolerated source of nutrition7
    • Easy-to-digest 60:40 whey-to-casein ratio, patterned after mature breast milk8,§
    • Inositol at the average amount found in breast milk#
    • Non-GMO
    • Kosher

    § Comparison based on whey:casin ratio of typical mature breast milk (15 days to 6 months after birth)8.
    * Studies compared infants fed Enfamil® that had DHA and ARA vs. dicontinued Enfamil without DHA and ARA; studied before the addition of prebiotics.
    † Average amount of DHA in worldwide breast milk is 0.32% ± 0.22%(mean ± standard deviation of total fatty acids) based on an analysis of 65 studies of 2,474 women1.
    ‡Enfamil NeuroPro Infant has not been shown superior to the leading competitor in supporting mental, visual and immune system development in infants. The level of DHA in Similac Pro-Advance™ is ~0.15 of total fatty acids.
    || The global average total inositol amount in mature breast milk over the course of lactation is 22 mg/100 kcal9.
    Ingredients not genetically engineered. Trace amounts of genetically engineered material may be presented in the product, such as fro manufacturing environments and process sources. For more information, visit enfamil.com/nonGMO.

    Take a deeper look at how MFGM in infant formula supports cognitive development and immune health like breast milk2

    CLINICALLY SHOWN TO IMPROVE DEVELOPMENTAL MILESTONES AT YEAR ONE*2

    Neurodevelopment, Nutrition and Growth in Infants Fed Formula With MFGM

    This study was conducted regarding MFGM and is not specific to this product.

    *As measured by Bayley-III cognitive score at 12 months in a different formula with MFGM added as an ingredient compared to a standard formula without MFGM.

    Download

    Brain first nutrition

    CLINICALLY SHOWN TO SUPPORT IMMUNE HEALTH LIKE BREAST MILK4

    Decreased infections in infants fed formula supplemented with MFGM

    *Based on a study comparing a different formula with MFGM added as an ingredient to a standard formula without it.4 Measured at 6 months of age.

    This study was conducted regarding MFGM and is not specific to this product.

    Download

    References

     

    1. Brenna JT, Varamini B, Jensen RG, et al. Docosahexaenoic and arachidonic acid concentrations in human breast milk worldwide. Am J Clin Nutr. 2007;85:1457-1464.
    2. Colombo J, Carlson SE, Cheatham CL, et al. Long-term effects of LCPUFA supplementation on childhood cognitive outcomes. Am J Clin Nutr. 2013;98:403-412.
    3. Birch EE, Khoury JC, Berseth CL, et al. The impact of early nutrition on incidence of allergic manifestations and common respiratory illnesses in children. J Pediatr. 2010;156:902-906.
    4. Scalabrin D, Mitmesser SH,, Welling GW, et al. New prebiotic blend of polydextrose and galacto-oligosaccharides has a bifidogenic effect in young infants. J Pediatr Gastroenterol Nutr. 2012;54:343-352.
    5. Salminen S, Endo A, Isolauri E, et al. Early gut colonization with lactobacilli and staphylococcus in infants: the hygiene hypothesis extended. J Pediatr Gastroenterol Nutr. 2016;62:80-86.
    6. Ziegler E, Vanderhoof JA, Petschow B, et al. Term infants fed formula supplemented with selected blends of prebiotics grow normally and have soft stools similar to those reported for breast-fed infants. J Pediatr Gastroenterol Nutr. 2007;44:359-364.
    7. Timby N, Domellöf E, Hernell O, et al. Neurodevelopment, nutrition, and growth until 12 mo of age in infants fed a low-energy, low-protein formula supplemented with bovine milk fat globule membranes: a randomized controlled trial. Am J Clin Nutr. 2014;99:860-868.
    8. Kunz C, Lönnerdal B. Re-evaluation of the whey protein/casein ratio of human milk. Acta Paediatr. 192;81:107-112.
    9. Data on file.